D-dimer and fibrinogen
D-dimer Mathematics!
Fibrinogen = 3 domains = central E + 2D
Thrombin cleaves fibrino-peptides (A and B) in E = Fibrin monomers
With fibrin-peptides A and B gone the monomers can polympermize
Fibrin monomers polymerize = Fibrin polymers
FXIIIa crosslinks D in polymers = (D-D)E-(DD)E... = cross linked fibrin and clot stabilized!
!
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