Learn Mature B-cell Leukemia flow patterns by CD5/CD10!

CD5+/CD10-:

• CLL = CD23+

• Leukemic mantle cell = CD23-, FMC7+,SOX11-

CD5-/CD10-:

• Hairy cell leukemia = CD11c+, CD123+, BRAF+

• HCLv = CD11c+, CD123-, BRAF-

• SMZL = HCV, del7q31, MYD88 mutated (subset)

• B-PLL = CD5+/-, TP53 mutated

• LPL = MYD88 mutated

CD5-/CD10+:

• Leukemic follicular

• Leukemic Burkitt

Atlas of Hematological Cytology