Papa Heme's Cheat Sheets - AML Edition!
aarongoodman.substack.com
AML
Pathogenesis:
Block in differentiation (transcription factor)
Proliferative mutation (tyrosine kinase)
Bone Marrow
Hypercellular
Full of blasts >20%(no maturation)
Age
Increases with age
Predominately disease of elderly
CBC
Leukocytosis
Anemia
Thrombocytopenia
Pancytopenia
Can have low, normal, or elevated WBC!!!
Disease Tempo:
Fast
Lymph node involvement:
Very very …
Keep reading with a 7-day free trial
Subscribe to Papa Heme's Educational Portal to keep reading this post and get 7 days of free access to the full post archives.